Variant Signed
how can you have both hemoglobin S as well as normal hemoglobin yet not show any signs of sickle cell anemia?
The results of Tara’s test indicate her red blood cells carry hemoglobin S as well as normal hemoglobin. She is a carrier of this variant form of protein yet doesnt show any symptoms of sickle cell anemia under normal circumstances. How do you explain this?
As far as I know, sickle cell anemia only occurs if both copies of the beta-globin gene are of the “sickle cell” variant.
The reason this variant is still common in certain areas (specifically those where malaria occurs) is because a single hemoglobin S producing gene leads to a mix of sickle cells and normal hemoglobin cells, and this protects against malaria without causing anemia.
If I have understood the process correctly. I am a layman, not a doctor.
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